GenoCAD Introduces Latest Combinatorial Design Tool to Boost User Productivity

By CIOReview | Monday, September 14, 2015

FREMONT, CA: In an effort to improve user productivity, GenoCAD, a provider of DNA design software tools, launches a new version of its flagship DNA design platform, to increase efficiency in protein expression optimization and decrease the chance of expensive errors for DNA synthesis orders.

The latest version offers more flexibility and efficiency in the design and has an edge over the traditional model, which relies on cutting and pasting DNA fragments manually.  The new approach breaks down complex DNA sequences into numerous genetic parts, which in turn can be recombined using specific sets of rules to ensure the resulting DNA constructs can be “read” by cells.

The new feature can generate up to 20,000 sequence variants at a time. The users can now create a sequence template and select a range of genetic parts that will fit into that template. GenoCAD will then automatically create a series of constructs, each of which contains one of the parts from the defined range and matches the rules set out by the template. Users can rapidly create many DNA designs with slight variations that will allow for better optimization. They can easily export the resulting combinatorial designs to FASTA, GenBank, and plain text files, as well as save them to their accounts for later use.

“Many of the additions, especially the combinatorial design tool, were made in response to feedback from and discussion with users. As a result, our software will help researchers on the leading edge of discovery to design the DNA sequences that will build the foundation for the next generation of biotechnology products,” says Jean Peccoud, CEO, GenoCAD.